Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 8/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18939233 | 1.00 | APLNR (0.50) | APLNRFAAHMGLLGABRPGABRD | |
| SCHEMBL18969643 | 0.87 | APLNR (0.51) | APLNRFAAHFABP3FABP4 | |
| SCHEMBL18939307 | 0.86 | APLNR (0.53) | APLNRFABP3FABP4 | |
| SCHEMBL29771934 | 0.86 | APLNR (0.53) | APLNRFABP3FABP4 | |
| SCHEMBL18969641 | 0.85 | FAAH (0.54) | FAAHMGLLFABP3FABP4CA9 | |
| SCHEMBL18939220 | 0.83 | APLNR (0.53) | APLNRFAAHFABP3FABP4 | |
| SCHEMBL29771936 | 0.83 | APLNR (0.53) | APLNRFAAHFABP3FABP4 | |
| SCHEMBL18939308 | 0.77 | KMT2A (0.46) | FAAHALDH1A1MAPK1ELANE | |
| SCHEMBL26643565 | 0.76 | KMT2A (0.45) | FAAHALDH1A1MAPK1 | |
| SCHEMBL18939348 | 0.76 | KMT2A (0.45) | FAAHALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602806-B | Improved apelin receptor (APJ) agonists and uses thereof | 研究三角协会 | 2022-07-12 | — | — | CN | disclosed |