SCHEMBL29772142

SCHEMBL29772142

C[C@@H](O)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 5/20 0.64
▸ TACR1 P25103 1/20 0.62
▸ C5AR1 P21730 1/20 0.59
▸ IL23R Q5VWK5 1/20 0.58
▸ AGTR1 P30556 1/20 0.58
▸ AGTR2 P50052 1/20 0.58
▸ NTSR2 O95665 2/20 0.57
▸ NTSR1 P30989 2/20 0.57
▸ SLC6A2 P23975 1/20 0.57
▸ SORT1 Q99523 1/20 0.56
▸ F2 P00734 1/20 0.56
▸ OPRM1 P35372 2/20 0.55
▸ NPFFR1 Q9GZQ6 2/20 0.55
▸ NPFFR2 Q9Y5X5 2/20 0.55
▸ ABCC2 Q92887 1/20 0.55
▸ OPRD1 P41143 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31331997 0.98 KISS1R (0.62) KISS1RTACR1C5AR1IL23RAGTR1
SCHEMBL34463648 0.93 KISS1R (0.62) KISS1RTACR1C5AR1IL23RAGTR1
SCHEMBL29598567 0.93 KISS1R (0.65) KISS1RTACR1C5AR1IL23RAGTR1
SCHEMBL31332280 0.91 KISS1R (0.64) KISS1RTACR1C5AR1IL23RAGTR1
SCHEMBL29973644 0.91 KISS1R (0.66) KISS1RC5AR1IL23RSLC6A2
SCHEMBL31468796 0.89 KISS1R (0.64) KISS1RC5AR1IL23R
SCHEMBL29660499 0.88 KISS1R (0.65) KISS1RTACR1C5AR1NTSR2NTSR1
SCHEMBL31410855 0.87 KISS1R (0.65) KISS1RC5AR1IL23R
SCHEMBL29683171 0.86 KISS1R (0.62) KISS1RSLC6A2OPRM1
SCHEMBL30023454 0.85 DPP3 (0.64) KISS1RC5AR1IL23RSLC6A2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024132726-A1 SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE UNIWERSYTET GDANSKI (PL) 2024-06-27 — — WO claimed
US-12411147-B2 Erythrocyte-derived extracellular vesicles and proteins associated with such vesicles as biomarkers for Parkinson's disease UNIVERSITé LAVAL (CA) 2025-09-09 — — US disclosed
CN-117186177-B Duck blood cell protein peptide with uric acid reducing activity and preparation method thereof 中国农业大学 2024-08-23 — — CN disclosed
CN-110997696-B Cosmetic composition for improving skin comprising fusion protein to which skin permeation promoting peptide is bound 株式会社LG生活健康 2024-03-05 — — CN disclosed
EP-3271728-B1 MATERIALS AND METHODS FOR DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE ELECTROPHORETICS LTD (GB) 2024-02-28 — — EP disclosed
US-20230408532-A1 ERYTHROCYTE-DERIVED EXTRACELLULAR VESICLES AND PROTEINS ASSOCIATED WITH SUCH VESICLES AS BIOMARKERS FOR PARKINSON'S DISEASE UNIVERSITé LAVAL (CA) 2023-12-21 — — US disclosed
CN-117186177-A Duck blood cell protein peptide with uric acid reducing activity and preparation method thereof 中国农业大学 2023-12-08 — — CN disclosed
CN-116670298-A Genetically modified yeast cells for hemoglobin production 克里希有限公司 2023-08-29 — — CN disclosed
US-11662352-B2 Erythrocyte-derived extracellular vesicles and proteins associated with such vesicles as biomarkers for parkinson's disease UNIVERSITé LAVAL (CA) 2023-05-30 — — US disclosed
CN-111518876-B Quantitative detection method for bovine-derived genomic DNA in bovine hemoglobin product and application of quantitative detection method 润方(北京)生物医药研究院有限公司(CN) 2023-01-13 — — CN disclosed
US-20220397576-A1 APPARATUSES AND METHODS FOR DETECTION OF PANCREATIC CANCER Reccan AB (SE) 2022-12-15 — — US disclosed
EP-4097480-A1 METHOD OF SCREENING FOR A CHRONIC KIDNEY DISEASE OR GLOMERULOPATHY, METHOD OF MONITORING A RESPONSE TO TREATMENT OF A CHRONIC KIDNEY DISEASE OR GLOMERULOPATHY IN A SUBJECT AND A METHOD OF TREATMENT OF A CHRONIC KIDNEY DISEASE OR GLOMERULOPATHY Warszawski Uniwersytet Medyczny (PL) 2022-12-07 — — EP disclosed
CN-109679984-B Application of plant as host in expression of hemoglobin 北京睿诚海汇健康科技有限公司 2022-08-02 — — CN disclosed
CN-108220246-B Compounds for improving viral transduction 蓝鸟生物公司 2022-07-12 — — CN disclosed
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