SCHEMBL31332280

SCHEMBL31332280

CC(C)C[C@H](N)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)[C@@H](C)O)C(C)C)C(C)C

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 5/20 0.64
▸ C5AR1 P21730 1/20 0.62
▸ AGTR2 P50052 2/20 0.61
▸ AGTR1 P30556 1/20 0.61
▸ NTSR2 O95665 2/20 0.59
▸ NTSR1 P30989 2/20 0.59
▸ TACR1 P25103 1/20 0.59
▸ NMBR P28336 2/20 0.57
▸ GRPR P30550 2/20 0.57
▸ IL23R Q5VWK5 1/20 0.57
▸ GNRHR P30968 1/20 0.56
▸ ABCC2 Q92887 1/20 0.56
▸ PTGS1 P23219 1/20 0.56
▸ SORT1 Q99523 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29598567 0.98 KISS1R (0.65) KISS1RC5AR1AGTR2AGTR1NTSR2
SCHEMBL34463648 0.93 KISS1R (0.62) KISS1RC5AR1AGTR2AGTR1NTSR2
SCHEMBL31331997 0.92 KISS1R (0.62) KISS1RC5AR1AGTR2AGTR1NTSR2
SCHEMBL29772142 0.91 KISS1R (0.64) KISS1RC5AR1AGTR2AGTR1NTSR2
SCHEMBL34470137 0.90 KISS1R (0.67) KISS1RC5AR1IL23R
SCHEMBL30023454 0.89 DPP3 (0.64) KISS1RC5AR1IL23R
Spinorphin SCHEMBL25217672 0.88 KISS1R (0.60) KISS1R
Spinorphin SCHEMBL29977609 0.88 KISS1R (0.60) KISS1R
Spinorphin SCHEMBL25273730 0.88 KISS1R (0.60) KISS1R
SCHEMBL29894426 0.87 NTSR1 (0.63) AGTR2AGTR1NTSR2NTSR1SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121873174-A Polypeptide composition with blood pressure reducing effect and preparation method and application thereof 上海市第六人民医院金山分院(上海健康医学院附属金山区中心医院、上海市金山区中心医院) 2026-04-17 — — CN disclosed
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR KISS1R 1232/4885C5AR1 204/4885AGTR2 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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