SCHEMBL34463648

SCHEMBL34463648

CC(C)[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)O)C(C)C

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 4/20 0.62
▸ C5AR1 P21730 1/20 0.61
▸ AGTR2 P50052 3/20 0.60
▸ AGTR1 P30556 1/20 0.60
▸ IL23R Q5VWK5 1/20 0.60
▸ TACR1 P25103 1/20 0.60
▸ DPP3 Q9NY33 3/20 0.60
▸ NTSR2 O95665 1/20 0.56
▸ NTSR1 P30989 1/20 0.56
▸ NMBR P28336 2/20 0.55
▸ GRPR P30550 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29598567 0.95 KISS1R (0.65) KISS1RC5AR1AGTR2AGTR1IL23R
SCHEMBL29772142 0.93 KISS1R (0.64) KISS1RC5AR1AGTR2AGTR1IL23R
SCHEMBL31332280 0.93 KISS1R (0.64) KISS1RC5AR1AGTR2AGTR1IL23R
SCHEMBL30023454 0.93 DPP3 (0.64) KISS1RC5AR1IL23RDPP3
SCHEMBL31331997 0.91 KISS1R (0.62) KISS1RC5AR1AGTR2AGTR1IL23R
SCHEMBL30268594 0.89 IL23R (0.66) KISS1RC5AR1IL23RDPP3
SCHEMBL38661114 0.88 KISS1R (0.62) KISS1RIL23RDPP3
SCHEMBL31307225 0.88 IL23R (0.65) KISS1RC5AR1IL23R
SCHEMBL31071616 0.87 DPP3 (0.73) KISS1RDPP3
SCHEMBL29804127 0.87 DPP3 (0.73) KISS1RDPP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121873174-A Polypeptide composition with blood pressure reducing effect and preparation method and application thereof 上海市第六人民医院金山分院(上海健康医学院附属金山区中心医院、上海市金山区中心医院) 2026-04-17 — — CN disclosed
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