Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 2/20 | 0.62 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.53 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068415 | 1.00 | ZDHHC7 (0.62) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9697068 | 0.98 | ZDHHC7 (0.66) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL7329329 | 0.94 | ZDHHC7 (0.55) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL2007637 | 0.94 | ZDHHC7 (0.55) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9691868 | 0.86 | ZDHHC7 (0.44) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL7894283 | 0.85 | ZDHHC7 (0.44) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL8785206 | 0.84 | ZDHHC7 (0.39) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL6474533 | 0.83 | ZDHHC7 (0.42) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9079671 | 0.82 | ZDHHC7 (0.46) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL27905397 | 0.82 | ZDHHC7 (0.46) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148459-A1 | CLASS OF NOVEL SMAD3 PROTEIN DEGRADERS AND APPLICATION THEREOF | 和径医药科技（上海）有限公司 | 2022-07-14 | — | — | WO | disclosed |