Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894283 | 0.94 | ZDHHC7 (0.44) | ZDHHC7MEN1GAAKMT2ALCK | |
| SCHEMBL343267 | 0.88 | ZDHHC7 (0.36) | ZDHHC7MEN1GAAKMT2ACA1 | |
| SCHEMBL8785206 | 0.86 | ZDHHC7 (0.39) | ZDHHC7MEN1GAAKMT2ALCK | |
| SCHEMBL2007637 | 0.85 | ZDHHC7 (0.55) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL7329329 | 0.85 | ZDHHC7 (0.55) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL29772196 | 0.83 | ZDHHC7 (0.62) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL10068415 | 0.83 | ZDHHC7 (0.62) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9697068 | 0.81 | ZDHHC7 (0.66) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL14037392 | 0.81 | CYP1A2 (0.44) | ZDHHC7GAAKMT2ATDP1 | |
| SCHEMBL30744785 | 0.81 | MEN1 (0.35) | MEN1GAAKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005122682-A2 | PROCESS FOR THE PREPARATION OF ESTERS OF PIPERAZIC ACID | RANBAXY LABORATORIES LIMITED (IN) | 2005-12-29 | — | — | WO | disclosed |
| US-6180611-B1 | INHIBITORS OF MATRIX METALLOPROTEINASES AND TUMOR NECROSIS FACTOR | DARWIN DISCOVERY, LTD. (GB) | 2001-01-30 | — | — | US | disclosed |
| US-5994312-A | Peptidyl compounds | DARWIN DISCOVERY, LTD. (GB) | 1999-11-30 | — | — | US | disclosed |