Sugi Predict

Sugi Predict / Compounds / SCHEMBL2007637

SCHEMBL2007637

SCHEMBL2007637

CCCCC(Br)C(=O)OC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ZDHHC7 Q9NXF8 1/20 0.55
▸ LCK P06239 1/20 0.46
▸ PPARD Q03181 1/20 0.46
▸ ZDHHC20 Q5W0Z9 1/20 0.46
▸ ZDHHC2 Q9UIJ5 1/20 0.46
▸ CA2 P00918 4/20 0.44
▸ CA1 P00915 2/20 0.44
▸ CTSK P43235 9/20 0.42
▸ CTSS P25774 1/20 0.40
▸ TSHR P16473 2/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ ATM Q13315 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7329329 1.00 ZDHHC7 (0.55) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL29772196 0.94 ZDHHC7 (0.62) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL10068415 0.94 ZDHHC7 (0.62) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL9697068 0.93 ZDHHC7 (0.66) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL9691868 0.88 ZDHHC7 (0.44) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL8785206 0.86 ZDHHC7 (0.39) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL6474533 0.85 ZDHHC7 (0.42) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL7894283 0.83 ZDHHC7 (0.44) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL25670282 0.82 CA2 (0.53) CA2CA1CTSKCTSSATM
SCHEMBL14037392 0.81 CYP1A2 (0.44) ZDHHC7CTSKTSHRCYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282748-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2025-09-11 — — US disclosed
CN-118084871-B Compound for targeted degradation of c-Met protein and preparation method and application thereof 中国药科大学 2024-07-09 — — CN disclosed
CN-118084871-A Compound for targeted degradation of c-Met protein and preparation method and application thereof 中国药科大学 2024-05-28 — — CN disclosed
CN-113292539-B Substituted oxopyridine derivatives 拜耳制药股份公司 2023-12-22 — — CN disclosed
US-20230024752-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2023-01-26 — — US disclosed
US-20230024752-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2023-01-26 — — US disclosed
CN-114207524-A Resin composition, dry film, resist film, compound, acid generator, and method for producing N-organic sulfonyloxy compound 东京应化工业株式会社 2022-03-18 — — CN disclosed
CN-108699106-B Novel trifluoromethylpropionamide derivatives as HTRA1 inhibitors 豪夫迈·罗氏有限公司 2021-11-30 — — CN disclosed
US-11180471-B2 Substituted oxopyridine derivatives BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2021-11-23 — — US disclosed
US-11180471-B2 Substituted oxopyridine derivatives BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2021-11-23 — — US disclosed
EP-1689742-B1 QUINOLONECARBOXYLIC ACID COMPOUNDS HAVING 5-HT4 RECEPTOR AGONISTIC ACTIVITY PFIZER (US) 2010-03-17 — — EP disclosed
US-20080255113-A1 Quinolonecarboxylic Acid Compounds Having 5-Ht4 Receptor Agonistic Activity KATO TOMOKI 2008-10-16 — — US disclosed
US-20080194536-A1 Cyanoarylamines SMITHKLINE BEECHAM CORPORATION 2008-08-14 — — US disclosed
EP-1871379-A2 CYANOARYLAMINES Smithkline Beecham Corporation (US) 2008-01-02 — — EP disclosed
US-7148240-B2 Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same SANOFI-AVENTIS (FR) 2006-12-12 — — US disclosed
WO-2006113552-A2 CYANOARYLAMINES SMITHKLINE BEECHAM CORPORATION (US) 2006-10-26 — — WO disclosed
EP-1689742-A1 QUINOLONECARBOXYLIC ACID COMPOUNDS HAVING 5-HT4 RECEPTOR AGONISTIC ACTIVITY Pfizer, Inc. (US) 2006-08-16 — — EP disclosed
WO-2005049608-A1 QUINOLONECARBOXYLIC ACID COMPOUNDS HAVING 5-HT4 RECEPTOR AGONISTIC ACTIVITY PFIZER JAPAN, INC. (JP) 2005-06-02 — — WO disclosed
US-20040010011-A1 Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same SANOFI (FR) 2004-01-15 — — US disclosed
US-20020094586-A1 Detection of analytes SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2002-07-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080255113-A1 Quinolonecarboxylic Acid Compounds Having 5-Ht4 Receptor Agonistic Activity HTR4, HRH4, HRH2 ZDHHC7 3739/4885LCK 3578/4885PPARD 1457/4885
US-20040010011-A1 Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same ABAT, TNNT2, BCAT1 ZDHHC7 1603/4885LCK 1186/4885PPARD 1821/4885
US-11180471-B2 Substituted oxopyridine derivatives OGFOD1, VASP, PNPO ZDHHC7 4218/4885LCK 1113/4885PPARD 160/4885
US-20080194536-A1 Cyanoarylamines EDNRA, CYP19A1, HSD17B11 ZDHHC7 3120/4885LCK 3819/4885PPARD 4061/4885
US-20250282748-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES OGFOD1, VASP, PNPO ZDHHC7 4218/4885LCK 1113/4885PPARD 160/4885
US-20020094586-A1 Detection of analytes AKR7A2, DDX6, ANXA6 ZDHHC7 2742/4885LCK 4507/4885PPARD 4142/4885
US-20230024752-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES OGFOD1, VASP, PNPO ZDHHC7 4218/4885LCK 1113/4885PPARD 160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.