Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 9/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007637 | 1.00 | ZDHHC7 (0.55) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL29772196 | 0.94 | ZDHHC7 (0.62) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL10068415 | 0.94 | ZDHHC7 (0.62) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9697068 | 0.93 | ZDHHC7 (0.66) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9691868 | 0.88 | ZDHHC7 (0.44) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL8785206 | 0.86 | ZDHHC7 (0.39) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL6474533 | 0.85 | ZDHHC7 (0.42) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL7894283 | 0.83 | ZDHHC7 (0.44) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL25670282 | 0.82 | CA2 (0.53) | CA2CA1CTSKCTSSATM | |
| SCHEMBL14037392 | 0.81 | CYP1A2 (0.44) | ZDHHC7CTSKTSHRCYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530161-A | TREATING RHEUMATOID ARTHRITIS, PROMOTING WOUND HEALING | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1996-06-25 | — | — | US | disclosed |
| US-5514677-A | Hydroxamic acid based collagenase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-05-07 | — | — | US | disclosed |
| US-5310763-A | Wound healing, rheumatoid arthritis | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-10 | — | — | US | disclosed |
| US-5304604-A | Treating diseases involving tissue degradation, promoting wound healing | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-04-19 | — | — | US | disclosed |
| EP-0446267-B1 | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS | BRITISH BIO TECHNOLOGY (GB) | 1994-04-13 | — | — | EP | disclosed |
| EP-0445206-B1 | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS | BRITISH BIO TECHNOLOGY (GB) | 1994-03-16 | — | — | EP | disclosed |
| US-5240958-A | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-31 | — | — | US | disclosed |
| EP-0445206-A1 | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS. | BRITISH BIO TECHNOLOGY (GB) | 1991-09-11 | — | — | EP | disclosed |
| WO-1990005719-A1 | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-05-31 | — | — | WO | disclosed |
| WO-1990005716-A1 | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-05-31 | — | — | WO | disclosed |