Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542251 | 0.83 | GAA (0.71) | GAAMEN1KMT2APOLBPTGS2 | |
| SCHEMBL7524997 | 0.81 | MEN1 (0.54) | GAAMEN1KMT2APOLBPTGS2 | |
| SCHEMBL2236986 | 0.81 | MEN1 (0.66) | GAAMEN1KMT2APOLBKDM4E | |
| SCHEMBL9621731 | 0.81 | DBH (0.39) | GAAMEN1KMT2APOLBKDM4E | |
| SCHEMBL8322730 | 0.80 | MEN1 (0.68) | GAAMEN1KMT2APOLBPTGS2 | |
| SCHEMBL207179 | 0.80 | GAA (0.62) | GAAMEN1KMT2APOLBPTGS2 | |
| SCHEMBL6929324 | 0.78 | GAA (0.60) | GAAMEN1KMT2APOLBPTGS2 | |
| SCHEMBL8026574 | 0.78 | GAA (0.60) | GAAMEN1KMT2APOLBPTGS2 | |
| SCHEMBL12473173 | 0.78 | PTGS2 (0.61) | GAAMEN1KMT2APOLBPTGS2 | |
| Hydrochloric Acid SCHEMBL8410665 | 0.78 | GAA (0.65) | GAAMEN1KMT2APOLBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781445-B2 | Synthesis of indenoisoquinoliniums and methods of use | PURDUE RESEARCH FOUNDATION (US) | 2010-08-24 | — | — | US | disclosed |
| US-20080242692-A1 | Synthesis of Indenoisoquinoliniums and Methods of Use | PURDUE RESEARCH FOUNDATION | 2008-10-02 | — | — | US | disclosed |
| EP-1735281-A2 | SYNTHESIS OF INDENOISOQUINOLINIUMS AND METHODS OF USE | Purdue Research Foundation (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005089294-A2 | SYNTHESIS OF INDENOISOQUINOLINIUMS AND METHODS OF USE | PURDUE RESEARCH FOUNDATION (US) | 2005-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242692-A1 | Synthesis of Indenoisoquinoliniums and Methods of Use | INMT, QTRT1, QTRT2 | GAA 2336/4885MEN1 59/4885KMT2A 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.