Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905863 | 0.92 | CHRM2 (0.49) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL13696680 | 0.87 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL30022454 | 0.87 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL19806740 | 0.84 | DDB1 (0.42) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL16597821 | 0.83 | GABRG2 (0.42) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL31017644 | 0.80 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL20581212 | 0.78 | GABRG2 (0.43) | MAOAMAOBACHEGABRG2GABRB3 | |
| SCHEMBL23392066 | 0.78 | NR1H2 (0.48) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL18012185 | 0.78 | GABRG2 (0.41) | GABRG2GABRB3GABRA5GPR119GABRA1 | |
| SCHEMBL30754584 | 0.78 | NR1H2 (0.48) | GABRG2GABRB3GABRA5GABRA1GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-114867727-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-08-05 | — | — | CN | disclosed |