SCHEMBL29774503

SCHEMBL29774503

CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2/C=N/OCc1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 17/20 0.81
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
ALDH1A1 P00352 3/20 0.60
GLA P06280 3/20 0.60
KDM4E B2RXH2 2/20 0.60
TP53 P04637 2/20 0.60
HPGD P15428 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
HDAC1 Q13547 2/20 0.60
HDAC2 Q92769 2/20 0.60
HDAC10 Q969S8 2/20 0.60
HDAC6 Q9UBN7 2/20 0.60
STAT6 P42226 1/20 0.60
CHEK1 O14757 1/20 0.60
HDAC3 O15379 1/20 0.60
ABCC4 O15439 1/20 0.60
GMNN O75496 1/20 0.60
LMNA P02545 1/20 0.60
CYP1A2 P05177 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2025479 1.00 TOP1 (0.81) TOP1MEN1KMT2AALDH1A1GLA
SCHEMBL3182211 0.96 TOP1 (0.77) TOP1MEN1KMT2AALDH1A1GLA
SCHEMBL3181074 0.94 TOP1 (0.75) TOP1MEN1KMT2AALDH1A1GLA
SCHEMBL2028388 0.93 TOP1 (0.85) TOP1MEN1KMT2AALDH1A1GLA
SCHEMBL25130176 0.93 TOP1 (0.85) TOP1MEN1KMT2AALDH1A1GLA
SCHEMBL3195114 0.93 TOP1 (0.73) TOP1MEN1KMT2AALDH1A1GLA
SCHEMBL13944309 0.92 TOP1 (0.88) TOP1MEN1KMT2AALDH1A1GLA
SCHEMBL2026258 0.91 TOP1 (0.81) TOP1MEN1KMT2AALDH1A1GLA
SCHEMBL22843988 0.91 TOP1 (0.81) TOP1MEN1KMT2AALDH1A1GLA
SCHEMBL2028767 0.91 TOP1 (0.81) TOP1MEN1KMT2AALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250144021-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2025-05-08 US disclosed
EP-4529468-A1 FORMULATION OF API'S AND EXCIPIENT'S IN AN ICELL VIA HYDROPHOBIC ION PAIRING Danmarks Tekniske Universitet (DK) 2025-04-02 EP disclosed
EP-4529477-A1 POROUS EXPANDING BIOCOMPATIBLE SCAFFOLDS Danmarks Tekniske Universitet (DK) 2025-04-02 EP disclosed
WO-2025062083-A1 METHOD FOR PRODUCING A COMPARTMENTED TANK MADE OF COMPOSITE MATERIAL ARIANEGROUP SAS (FR) 2025-03-27 WO disclosed
WO-2025062086-A1 METHOD FOR PRODUCING A TANK MADE OF COMPOSITE MATERIAL WITH SIMPLIFIED MOULDING EQUIPMENT ARIANEGROUP SAS (FR) 2025-03-27 WO disclosed
WO-2025062092-A1 METHOD FOR PRODUCING A COMPARTMENTED TANK MADE OF COMPOSITE MATERIAL ARIANEGROUP SAS (FR) 2025-03-27 WO disclosed
US-12226527-B2 Gel formulations for local drug release TECHNICAL UNIVERSITY OF DENMARK (DK) 2025-02-18 US disclosed
US-12042560-B2 Liposome composition EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-07-23 US disclosed
WO-2023227518-A1 POROUS EXPANDING BIOCOMPATIBLE SCAFFOLDS DANMARKS TEKNISKE UNIVERSITET (DK) 2023-11-30 WO disclosed
WO-2023227517-A1 FORMULATION OF API'S AND EXCIPIENT'S IN AN ICELL VIA HYDROPHOBIC ION PAIRING DANMARKS TEKNISKE UNIVERSITET (DK) 2023-11-30 WO disclosed
EP-4282448-A1 POROUS EXPANDING BIOCOMPATIBLE SCAFFOLDS Danmarks Tekniske Universitet (DK) 2023-11-29 EP disclosed
EP-4282435-A1 FORMULATIONS OF ACTIVE PHARMACEUTICAL INGREDIENTS AND EXCIPIENTS IN ICELLS VIA HYDROPHOBIC ION PAIRING Danmarks Tekniske Universitet (DK) 2023-11-29 EP disclosed
CN-115501172-A Gel formulations for topical drug delivery 丹麦技术大学 2022-12-23 CN disclosed
US-20220339285-A1 DISSACHARIDE FORMULATIONS FOR CONTROLLED DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2022-10-27 US disclosed
CN-107249570-B Gel formulations for topical drug delivery 丹麦技术大学 2022-08-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250144021-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TREH, GALE, SLC2A8 TOP1 1369/4885MEN1 4426/4885KMT2A 4874/4885
US-12226527-B2 Gel formulations for local drug release TREH, GALE, SLC2A8 TOP1 1369/4885MEN1 4426/4885KMT2A 4874/4885
US-20220339285-A1 DISSACHARIDE FORMULATIONS FOR CONTROLLED DRUG RELEASE LIPA, LIPE, CEL TOP1 2058/4885MEN1 4853/4885KMT2A 3321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.