Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 5/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23212666 | 1.00 | GABRA5 (0.33) | GABRA5PTK2GRIA2TGFBR1L3MBTL1 | |
| SCHEMBL24926786 | 0.87 | TGFBR1 (0.33) | GABRA5PTK2GRIA2TGFBR1L3MBTL1 | |
| SCHEMBL29776219 | 0.84 | ADRB2 (0.36) | GABRA5GRIA2TGFBR1GRM5PLAU | |
| SCHEMBL22498513 | 0.84 | ADRB2 (0.36) | GABRA5GRIA2TGFBR1GRM5PLAU | |
| SCHEMBL29659908 | 0.84 | ADRB2 (0.36) | GABRA5GRIA2TGFBR1GRM5PLAU | |
| SCHEMBL29776082 | 0.78 | DYRK1A (0.42) | GRM5 | |
| SCHEMBL23212759 | 0.78 | DYRK1A (0.42) | GRM5 | |
| SCHEMBL23212679 | 0.77 | KDM4E (0.39) | L3MBTL1 | |
| SCHEMBL29775988 | 0.77 | KDM4E (0.39) | L3MBTL1 | |
| SCHEMBL29776123 | 0.74 | HRH1 (0.33) | GRIA2TGFBR1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761393-A | Heteroaryl substituted pyrazine derivatives as pesticides | 拜耳动物保健有限责任公司 | 2022-07-15 | — | — | CN | disclosed |