Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthoquinone SCHEMBL820053 | 1.00 | IDO1 (0.42) | IDO1MAOAMAOBCDC25BSNCA | |
| SCHEMBL318571 | 0.80 | ALDH1A1 (0.33) | ALDH1A1POLBNPSR1MAPTKDM4E | |
| Naphthoquinone SCHEMBL29639242 | 0.75 | DPP4 (0.44) | IDO1MAOAMAOBCDC25BSNCA | |
| Naphthoquinone SCHEMBL1820512 | 0.75 | DPP4 (0.44) | IDO1MAOAMAOBCDC25BSNCA | |
| Naphthoquinone SCHEMBL27458460 | 0.68 | CDC25B (0.74) | IDO1MAOAMAOBCDC25BSNCA | |
| Naphthoquinone SCHEMBL28300816 | 0.66 | CDC25B (0.70) | IDO1MAOAMAOBCDC25BSNCA | |
| SCHEMBL19838232 | 0.66 | KMT2A (0.55) | ALDH1A1L3MBTL1MEN1KMT2APOLB | |
| Naphthoquinone SCHEMBL29148785 | 0.65 | IDO1 (0.88) | IDO1MAOAMAOBCDC25BSNCA | |
| Naphthoquinone SCHEMBL29354680 | 0.65 | IDO1 (1.00) | IDO1MAOAMAOBCDC25BSNCA | |
| Naphthoquinone SCHEMBL11359780 | 0.65 | IDO1 (1.00) | IDO1MAOAMAOBCDC25BSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024256574-A1 | PROCESS FOR PREPARING MACROCYCLIC BTK INHIBITORS | CROSSFIRE ONCOLOGY HOLDING B.V. (NL) | 2024-12-19 | — | — | WO | claimed |
| US-20240300922-A1 | PROCESS FOR PREPARING EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2024-09-12 | — | — | US | claimed |
| US-20220396576-A1 | PROCESS FOR PREPARING AN ACTIVIN RECEPTOR-LIKE KINASE INHIBITOR | BLUEPRINT MEDICINES CORPORATION | 2022-12-15 | — | — | US | claimed |
| EP-4038071-A1 | PROCESS FOR PREPARING AN ACTIVIN RECEPTOR-LIKE KINASE INHIBITOR | Blueprint Medicines Corporation (US) | 2022-08-10 | — | — | EP | claimed |
| EP-4038071-B1 | PROCESS FOR PREPARING AN ACTIVIN RECEPTOR-LIKE KINASE INHIBITOR | BLUEPRINT MEDICINES CORP (US) | 2024-12-18 | — | — | EP | disclosed |
| US-20220396576-A1 | PROCESS FOR PREPARING AN ACTIVIN RECEPTOR-LIKE KINASE INHIBITOR | BLUEPRINT MEDICINES CORPORATION | 2022-12-15 | — | — | US | disclosed |
| US-20220389310-A1 | LUMINESCENT MATERIALS AND METHODS THEREOF | UNIVERSITY OF WASHINGTON (US) | 2022-12-08 | — | — | US | disclosed |
| EP-4038071-A1 | PROCESS FOR PREPARING AN ACTIVIN RECEPTOR-LIKE KINASE INHIBITOR | Blueprint Medicines Corporation (US) | 2022-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300922-A1 | PROCESS FOR PREPARING EGFR INHIBITORS | EGFR, ERBB2, ERBB4 | IDO1 3497/4885MAOA 2182/4885MAOB 1446/4885 |
| US-20220389310-A1 | LUMINESCENT MATERIALS AND METHODS THEREOF | TYR, GSTA2, CYBA | IDO1 898/4885MAOA 158/4885MAOB 247/4885 |
| US-20220396576-A1 | PROCESS FOR PREPARING AN ACTIVIN RECEPTOR-LIKE KINASE INHIBITOR | ACVR1, ACVRL1, BMP2K | IDO1 705/4885MAOA 538/4885MAOB 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.