Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | DDO | Q99489 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TYMS | P04818 | 3/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29778097 | 0.83 | MAPT (0.50) | KDM4EDAODDOALDH1A1HPGD | |
| SCHEMBL29778146 | 0.80 | CYP11B2 (0.44) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL28778241 | 0.79 | CYP1A2 (0.36) | KDM4EALDH1A1HPGDTYMSMAPT | |
| SCHEMBL29778152 | 0.79 | CYP1A2 (0.36) | KDM4EALDH1A1HPGDTYMSMAPT | |
| SCHEMBL24289840 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL14765152 | 0.77 | BRD4 (0.53) | KDM4EDAOTYMSBRD4 | |
| SCHEMBL9949706 | 0.76 | ALDH1A1 (0.59) | KDM4EDAOALDH1A1HPGDPDE3B | |
| SCHEMBL29778151 | 0.75 | GRIN2D (0.54) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL29778110 | 0.75 | CYP1A2 (0.53) | KDM4EPDE3BPDE3AMAPTMEN1 | |
| SCHEMBL29037515 | 0.75 | GRIN2D (0.54) | KDM4EALDH1A1HPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685384-B | Difluoromethyl reaction method and application thereof | 深圳大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-114685384-A | Difluoromethyl reaction method and application thereof | 深圳大学 | 2022-07-01 | — | — | CN | disclosed |