Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18059295 | 1.00 | ALOX5 (0.53) | ALOX5MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL18041364 | 0.85 | BCHE (0.51) | ALOX5MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29664574 | 0.85 | BCHE (0.51) | ALOX5MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20819271 | 0.84 | ALOX5 (0.52) | ALOX5MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20819279 | 0.84 | ALOX5 (0.47) | ALOX5MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3064038 | 0.84 | ALDH1A1 (0.54) | ALOX5MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL18041442 | 0.84 | RAB9A (0.52) | RAB9ASMN1; SMN2MAOBMAOAACHE | |
| SCHEMBL18059296 | 0.82 | IDO1 (0.47) | SMN1; SMN2IDO1BCHECNR2LMNA | |
| SCHEMBL29778177 | 0.82 | IDO1 (0.47) | SMN1; SMN2IDO1BCHECNR2LMNA | |
| SCHEMBL1019102 | 0.81 | MAPT (0.55) | ALOX5MAPTRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4038053-A1 | AMIDE-LINKED, AMINOBENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | Bolt Biotherapeutics, Inc. (US) | 2022-08-10 | — | — | EP | disclosed |