Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 10/20 | 0.48 |
| ▸ | CA1 | P00915 | 9/20 | 0.48 |
| ▸ | CA12 | O43570 | 7/20 | 0.48 |
| ▸ | CA9 | Q16790 | 7/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 2/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12502050 | 1.00 | MAOA (0.62) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL1419813 | 0.98 | MAOA (0.65) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL19965900 | 0.98 | MAOA (0.60) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL9726174 | 0.97 | MAOA (0.68) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL10688506 | 0.97 | MAOA (0.68) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL4730562 | 0.97 | MAOA (0.67) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL1273886 | 0.95 | MAOA (0.65) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL3290430 | 0.95 | MAOA (0.56) | MAOAMAOBTDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8724041 | 0.95 | MAOA (0.65) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL7203519 | 0.95 | MAOA (0.64) | MAOAMAOBTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999345-B1 | COMPOSITIONS AND METHODS COMPRISING A POLYAMINE | CURZA GLOBAL LLC (US) | 2022-08-10 | — | — | EP | disclosed |