Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 10/20 | 0.48 |
| ▸ | CA1 | P00915 | 9/20 | 0.48 |
| ▸ | CA12 | O43570 | 7/20 | 0.48 |
| ▸ | CA9 | Q16790 | 7/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 2/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29778251 | 1.00 | MAOA (0.62) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL1419813 | 0.98 | MAOA (0.65) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL19965900 | 0.98 | MAOA (0.60) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL9726174 | 0.97 | MAOA (0.68) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL10688506 | 0.97 | MAOA (0.68) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL4730562 | 0.97 | MAOA (0.67) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL1273886 | 0.95 | MAOA (0.65) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL3290430 | 0.95 | MAOA (0.56) | MAOAMAOBTDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8724041 | 0.95 | MAOA (0.65) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL7203519 | 0.95 | MAOA (0.64) | MAOAMAOBTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260132164-A1 | PNU ANTHRACYCLINE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2026-05-14 | — | — | US | disclosed |
| EP-4704914-A1 | ANTI-TROP2 ANTIBODY-DRUG CONJUGATES COMPRISING PNU-159682 DERIVATIVES | Merck Sharp & Dohme LLC (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-4608398-A1 | PNU ANTHRACYCLINE DERIVATIVES AND METHODS OF USE THEREOF | Merck Sharp & Dohme LLC (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024226388-A1 | ANTI-TROP2 ANTIBODY-DRUG CONJUGATES COMPRISING PNU-159682 DERIVATIVES | MERCK SHARP & DOHME LLC (US) | 2024-10-31 | — | — | WO | disclosed |
| WO-2024091894-A1 | PNU ANTHRACYCLINE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-05-02 | — | — | WO | disclosed |
| US-20230242474-A1 | LIPID COMPOUND AND THE COMPOSITION THEREOF | GUANGZHOU RIBOBIO CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
| US-20230149550-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
| EP-2999345-B1 | COMPOSITIONS AND METHODS COMPRISING A POLYAMINE | CURZA GLOBAL LLC (US) | 2022-08-10 | — | — | EP | disclosed |
| WO-2020201525-A1 | MULTIFUNCTIONAL COMPOUNDS FOR POLYMER MATRIX GRAFTING | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2020-10-08 | — | — | WO | disclosed |
| US-10440955-B2 | Methods comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2019-10-15 | — | — | US | disclosed |
| US-20150038705-A1 | METHODS OF USE COMPRISING A BIOCIDAL POLYAMINE | CURZA GLOBAL, LLC | 2015-02-05 | — | — | US | disclosed |
| US-20150038455-A1 | HEPARAN SULFATE/HEPARIN MIMETICS WITH ANTI-CHEMOKINE AND ANTI-INFLAMMATORY ACTIVITY | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2015-02-05 | — | — | US | disclosed |
| US-20150038436-A1 | TAILORED GLYCOPOLYMERS AS ANTICOAGULANT HEPARIN MIMETICS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2015-02-05 | — | — | US | disclosed |
| US-20150038512-A1 | COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE | THE UNIVERSITY OF UTAH | 2015-02-05 | — | — | US | disclosed |
| US-20150038705-A1 | METHODS OF USE COMPRISING A BIOCIDAL POLYAMINE | CURZA GLOBAL, LLC | 2015-02-05 | — | — | US | disclosed |
| US-20140350017-A1 | METHODS OF USE FOR COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | THE UNIVERSITY OF UTAH (US) | 2014-11-27 | — | — | US | disclosed |
| US-20140350017-A1 | METHODS OF USE FOR COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | THE UNIVERSITY OF UTAH (US) | 2014-11-27 | — | — | US | disclosed |
| US-8853278-B1 | Compositions comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2014-10-07 | — | — | US | disclosed |
| US-8853278-B1 | Compositions comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2014-10-07 | — | — | US | disclosed |
| WO-2012104788-A2 | ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149550-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | DMPK, DTYMK, MYCBP | MAOA 2137/4885MAOB 1592/4885TDP1 70/4885 |
| US-20140350017-A1 | METHODS OF USE FOR COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | SRM, SMOX, SMS | MAOA 113/4885MAOB 76/4885TDP1 440/4885 |
| US-20150038705-A1 | METHODS OF USE COMPRISING A BIOCIDAL POLYAMINE | SRM, SMOX, SMS | MAOA 125/4885MAOB 77/4885TDP1 532/4885 |
| US-20150038455-A1 | HEPARAN SULFATE/HEPARIN MIMETICS WITH ANTI-CHEMOKINE AND ANTI-INFLAMMATORY ACTIVITY | CCL2, CCL5, ACKR3 | MAOA 4414/4885MAOB 4354/4885TDP1 3244/4885 |
| US-10440955-B2 | Methods comprising a biocidal polyamine | SRM, SMOX, SMS | MAOA 116/4885MAOB 81/4885TDP1 419/4885 |
| US-20230242474-A1 | LIPID COMPOUND AND THE COMPOSITION THEREOF | NPC1L1, NPC1, SGMS1 | MAOA 4163/4885MAOB 3871/4885TDP1 4847/4885 |
| US-20260132164-A1 | PNU ANTHRACYCLINE DERIVATIVES AND METHODS OF USE THEREOF | TOP1, NCL, NOLC1 | MAOA 3549/4885MAOB 2895/4885TDP1 216/4885 |
| US-20150038436-A1 | TAILORED GLYCOPOLYMERS AS ANTICOAGULANT HEPARIN MIMETICS | GYPA, FUT6, FUT5 | MAOA 2615/4885MAOB 2625/4885TDP1 1293/4885 |
| US-20150038512-A1 | COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE | SRM, SMOX, SMS | MAOA 110/4885MAOB 89/4885TDP1 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.