Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 12/20 | 0.49 |
| ▸ | CA1 | P00915 | 11/20 | 0.49 |
| ▸ | CA12 | O43570 | 8/20 | 0.49 |
| ▸ | CA9 | Q16790 | 8/20 | 0.49 |
| ▸ | STK17B | O94768 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12502050 | 0.95 | MAOA (0.62) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL29778251 | 0.95 | MAOA (0.62) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL1419813 | 0.93 | MAOA (0.65) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL1273886 | 0.93 | MAOA (0.65) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL17263661 | 0.93 | MAOA (0.69) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL19965900 | 0.93 | MAOA (0.60) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL1557057 | 0.93 | TDP1 (0.67) | MAOAMAOBTDP1MEN1GAA | |
| Hydrochloric Acid SCHEMBL8724039 | 0.92 | MAOA (0.63) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL9726174 | 0.92 | MAOA (0.68) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL10688506 | 0.92 | MAOA (0.68) | MAOAMAOBTDP1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048315-A2 | ANTISENSE MODULATION OF MDM2 EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2003-06-12 | — | — | WO | disclosed |