Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.63 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rubrofusarin B SCHEMBL16227248 | 1.00 | XDH (1.00) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| SCHEMBL15060666 | 0.88 | XDH (0.79) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| Rubrofusarin SCHEMBL486101 | 0.88 | XDH (0.79) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| SCHEMBL8860356 | 0.85 | XDH (0.74) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| SCHEMBL8833383 | 0.83 | XDH (0.70) | XDHPTGS1PTGS2KDM4ELMNA | |
| SCHEMBL16226550 | 0.83 | XDH (0.70) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| Aurasperone A SCHEMBL29779131 | 0.80 | XDH (0.80) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| SCHEMBL8860230 | 0.80 | XDH (0.67) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| Asperpyrone C SCHEMBL29779200 | 0.80 | XDH (0.73) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| SCHEMBL16226658 | 0.79 | ABCG2 (0.66) | XDHPTGS1PTGS2HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114848628-B | Application of naphtho gamma-pyrone compounds in preparation of anti-helicobacter pylori medicines or health care products | 暨南大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-114848628-A | Application of naphtho-gamma-pyrone compounds in preparation of anti-helicobacter pylori medicines or prevention health-care products | 暨南大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-113444644-B | Application of naphtho-gamma-pyrone compounds in preparation of anti-helicobacter pylori medicines or prevention health-care products | 暨南大学 | 2022-07-19 | — | — | CN | disclosed |