Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aurasperone A SCHEMBL29779131 | 0.94 | XDH (0.80) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| Fonsecinone A SCHEMBL29779161 | 0.84 | XDH (1.00) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| Asperpyrone A SCHEMBL29779212 | 0.80 | XDH (0.93) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| Rubrofusarin B SCHEMBL29779134 | 0.80 | XDH (1.00) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| Rubrofusarin B SCHEMBL16227248 | 0.80 | XDH (1.00) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| SCHEMBL8860230 | 0.76 | XDH (0.67) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| SCHEMBL8860356 | 0.74 | XDH (0.74) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| SCHEMBL8860537 | 0.73 | PTGS1 (0.64) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| SCHEMBL21638079 | 0.73 | XDH (0.64) | XDHPTGS1PTGS2HIF1AEPAS1 | |
| SCHEMBL29779171 | 0.73 | XDH (0.64) | XDHPTGS1PTGS2HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118562908-A | Preparation method and application of benzopyrone compound in Kandelia candel endophytic fungi | 海南师范大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-114848628-B | Application of naphtho gamma-pyrone compounds in preparation of anti-helicobacter pylori medicines or health care products | 暨南大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-114848628-A | Application of naphtho-gamma-pyrone compounds in preparation of anti-helicobacter pylori medicines or prevention health-care products | 暨南大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-113444644-B | Application of naphtho-gamma-pyrone compounds in preparation of anti-helicobacter pylori medicines or prevention health-care products | 暨南大学 | 2022-07-19 | — | — | CN | disclosed |