Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.48 |
| ▸ | BCAT1 | P54687 | 4/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15268658 | 0.86 | AR (0.75) | ARPOLBGAA | |
| SCHEMBL4178171 | 0.82 | AR (1.00) | ARPOLBGAASLC22A12BCAT1 | |
| SCHEMBL28625665 | 0.80 | AR (0.61) | ARPOLBGAASLC22A12BCAT1 | |
| SCHEMBL30730992 | 0.78 | ALDH1A1 (0.63) | ARPOLBGAAIMPDH2IMPDH1 | |
| SCHEMBL1762094 | 0.78 | ALDH1A1 (0.63) | ARPOLBGAAIMPDH2IMPDH1 | |
| SCHEMBL9560109 | 0.78 | MAOB (0.57) | ARPOLBGAAIMPDH2IMPDH1 | |
| SCHEMBL24824003 | 0.77 | AR (0.62) | ARBCAT1 | |
| SCHEMBL18615595 | 0.76 | IMPDH2 (0.62) | ARPOLBGAASLC22A12BCAT1 | |
| SCHEMBL13875554 | 0.76 | AR (0.69) | ARPOLBGAABCAT1 | |
| SCHEMBL4175953 | 0.76 | AR (1.00) | ARPOLBGAASLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4038054-A1 | PYRIMIDINEDIONE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2022-08-10 | — | — | EP | claimed |
| EP-4038054-A1 | PYRIMIDINEDIONE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2022-08-10 | — | — | EP | disclosed |