SCHEMBL1762094

SCHEMBL1762094

COc1ccc(OC)c(C#N)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
KDM4E B2RXH2 1/20 0.63
USP2 O75604 1/20 0.63
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
AR P10275 9/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
IMPDH2 P12268 1/20 0.53
IMPDH1 P20839 1/20 0.53
TP53 P04637 1/20 0.52
HSD17B10 Q99714 1/20 0.52
MAOB P27338 1/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
MEN1 O00255 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30730992 1.00 ALDH1A1 (0.63) ALDH1A1KDM4EUSP2CA12CA1
SCHEMBL9560109 0.91 MAOB (0.57) ALDH1A1KDM4EUSP2CA12CA1
SCHEMBL1608900 0.88 AR (0.69) ALDH1A1KDM4EUSP2CA12CA1
SCHEMBL30150440 0.84 NPC1 (0.51) ALDH1A1KDM4EUSP2CA12CA1
SCHEMBL14805868 0.83 ALDH1A1 (0.54) ALDH1A1KDM4EUSP2ARNPC1
SCHEMBL12299457 0.83 NPC1 (0.48) ALDH1A1KDM4EUSP2CA12CA1
SCHEMBL9034957 0.83 NPC1 (0.48) ALDH1A1KDM4EUSP2ARNPC1
SCHEMBL9034950 0.83 NPC1 (0.51) ALDH1A1KDM4EUSP2CA12CA1
SCHEMBL30313000 0.82 NPC1 (0.57) ALDH1A1KDM4EUSP2CA12CA1
SCHEMBL18927010 0.82 NPC1 (0.53) ALDH1A1KDM4EUSP2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713505-A1 ADDITIVES FOR IMPROVED ELECTROLYZER DURABILITY The Lubrizol Corporation (US) 2026-03-25 EP disclosed
US-20250129016-A1 PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-04-24 US disclosed
US-20250030008-A1 Carbon Supported Electrodes THE LUBRIZOL CORPORATION (US) 2025-01-23 US disclosed
WO-2024238744-A1 ADDITIVES FOR IMPROVED ELECTROLYZER DURABILITY THE LUBRIZOL CORPORATION (US) 2024-11-21 WO disclosed
EP-4434103-A1 CARBON SUPPORTED ELECTRODE The Lubrizol Corporation (US) 2024-09-25 EP disclosed
CN-118266106-A Carbon-loaded electrode 路博润公司 2024-06-28 CN disclosed
CN-117642379-A Phenylalkylamines and methods of making and using the same 吉尔伽美什制药公司 2024-03-01 CN disclosed
WO-2023091557-A1 CARBON SUPPORTED ELECTRODE THE LUBRIZOL CORPORATION (US) 2023-05-25 WO disclosed
CN-111635334-B Method for generating nitrile by catalyzing primary amine acceptor-free dehydrogenation through Ru complex 四川大学 2021-11-30 CN disclosed
CN-111635334-A Method for generating nitrile by catalyzing primary amine acceptor-free dehydrogenation through Ru complex 四川大学 2020-09-08 CN disclosed
CN-1604778-A Cis-imidazolines as MDM2 inhibitors HOFFMANN LA ROCHE (CH) 2005-04-06 CN disclosed
US-6875761-B2 Certain 1,3-disubstituted isoquinoline derivatives EISAI CO., LTD. (JP) 2005-04-05 US disclosed
US-20040204421-A1 Certain 1,3-disubstituted isoquinoline derivatives EISAI CO., LTD. 2004-10-14 US disclosed
EP-1463501-A1 CIS-IMIDAZOLINES AS MDM2 INHIBITORS F. Hoffmann-La Roche AG (CH) 2004-10-06 EP disclosed
US-6790844-B2 MUSCLE RELAXANTS; ANTISEROTONINE AGENT EISAI CO., LTD (JP) 2004-09-14 US disclosed
US-6617346-B1 Inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity HOFFMANN-LA ROCHE INC. 2003-09-09 US disclosed
WO-2003051360-A1 CIS-IMIDAZOLINES AS MDM2 INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2003-06-26 WO disclosed
US-20020013460-A1 Condensed pyridine compound EISAI CO., LTD 2002-01-31 US disclosed
US-6340759-B1 ANTISPASMODIC AGENTS EISAI CO., LTD. (JP) 2002-01-22 US disclosed
EP-1020445-A1 FUSED PYRIDINE DERIVATIVES Eisai Co., Ltd. (JP) 2000-07-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013460-A1 Condensed pyridine compound MUSK, HTR1A, PAX3 ALDH1A1 2989/4885KDM4E 1050/4885USP2 3459/4885
US-20250129016-A1 PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF RCC2, PPOX, FTO ALDH1A1 2660/4885KDM4E 290/4885USP2 4032/4885
US-20040204421-A1 Certain 1,3-disubstituted isoquinoline derivatives MUSK, HTR1A, RYR1 ALDH1A1 1071/4885KDM4E 1058/4885USP2 2242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.