Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197772 | 0.79 | SMN1; SMN2 (0.44) | MEN1KMT2AALDH1A1HSD17B10RXFP1 | |
| SCHEMBL3060275 | 0.79 | SMN1; SMN2 (0.44) | MEN1KMT2AALDH1A1HSD17B10RXFP1 | |
| SCHEMBL3060271 | 0.79 | SMN1; SMN2 (0.44) | MEN1KMT2AALDH1A1HSD17B10RXFP1 | |
| SCHEMBL11985533 | 0.78 | CNR2 (0.41) | ALDH1A1RXFP1 | |
| SCHEMBL29779383 | 0.77 | ALDH1A1 (0.51) | AKR1C3MEN1KMT2AALDH1A1PHGDH | |
| SCHEMBL22798963 | 0.75 | BRS3 (0.44) | MEN1KMT2AALDH1A1GPR183L3MBTL1 | |
| SCHEMBL3315348 | 0.74 | ALDH1A1 (0.42) | AKR1C3MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3312862 | 0.72 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1POLBNPC1 | |
| SCHEMBL14711760 | 0.71 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL9367926 | 0.71 | ADAM10 (0.44) | KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716370-A | Pyridine-containing polycyclic derivative inhibitor, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-07-08 | — | — | CN | disclosed |