Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20777320 | 1.00 | MEN1 (0.46) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL22074348 | 0.88 | LMNA (0.60) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL22074484 | 0.85 | NOTUM (0.46) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL20777380 | 0.84 | TRPM8 (0.45) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20777281 | 0.83 | TRPM8 (0.45) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL20777357 | 0.82 | TRPM8 (0.54) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL20777284 | 0.82 | MAPT (0.42) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL29779999 | 0.78 | DRD4 (0.34) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL20777282 | 0.75 | TRPM8 (0.56) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL29780001 | 0.75 | TRPM8 (0.56) | MEN1KMT2ALMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | BASF SE (DE) | 2022-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | TRPM8, TRPM7, TRPM5 | MEN1 376/4885KMT2A 3482/4885LMNA 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.