Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29052606 | 1.00 | CNR1 (0.41) | CNR1CNR2ABL1NPSR1L3MBTL1 | |
| SCHEMBL29781023 | 0.87 | MAPT (0.43) | CNR1CNR2ALDH1A1PANK3MAPT | |
| SCHEMBL29052540 | 0.87 | MAPT (0.43) | CNR1CNR2ALDH1A1PANK3MAPT | |
| SCHEMBL29781088 | 0.86 | CNR1 (0.41) | CNR1CNR2L3MBTL1NPBWR1MCHR1 | |
| SCHEMBL29052193 | 0.86 | CNR1 (0.41) | CNR1CNR2L3MBTL1NPBWR1MCHR1 | |
| SCHEMBL29052244 | 0.83 | MAPT (0.45) | CNR1CNR2NPSR1ALDH1A1PANK3 | |
| SCHEMBL29052205 | 0.83 | NPBWR1 (0.47) | ABL1ALDH1A1NPBWR1MCHR1GAA | |
| SCHEMBL29780914 | 0.81 | NPSR1 (0.40) | CNR1CNR2ABL1NPSR1L3MBTL1 | |
| SCHEMBL29052152 | 0.81 | NPSR1 (0.40) | CNR1CNR2ABL1NPSR1L3MBTL1 | |
| SCHEMBL29052133 | 0.73 | ALDH1A1 (0.41) | ALDH1A1PANK3GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022166610-A1 | PYRIDAZINONE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-08-11 | — | — | WO | disclosed |