Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CPA2 | P48052 | 1/20 | 0.38 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29714772 | 1.00 | CPB2 (0.43) | CPB2NMT2NMT1FOLH1GSR | |
| SCHEMBL29782763 | 0.91 | FOLH1 (0.51) | CPB2NMT2NMT1FOLH1GSR | |
| SCHEMBL16862515 | 0.89 | FOLH1 (0.49) | CPB2FOLH1GSRDPP4DPP8 | |
| SCHEMBL16862514 | 0.89 | FOLH1 (0.49) | CPB2FOLH1GSRDPP4DPP8 | |
| SCHEMBL29802019 | 0.88 | NMT2 (0.44) | CPB2NMT2NMT1FOLH1GSR | |
| SCHEMBL29353557 | 0.88 | NMT2 (0.44) | CPB2NMT2NMT1FOLH1GSR | |
| SCHEMBL1711315 | 0.88 | FOLH1 (0.54) | CPB2FOLH1GSRDPP4DPP8 | |
| SCHEMBL1711313 | 0.88 | FOLH1 (0.54) | CPB2FOLH1GSRDPP4DPP8 | |
| SCHEMBL29357446 | 0.88 | FOLH1 (0.54) | CPB2FOLH1GSRDPP4DPP8 | |
| SCHEMBL29358709 | 0.88 | FOLH1 (0.54) | CPB2FOLH1GSRDPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240277860-A1 | CAMPTOTHECIN PEPTIDE CONJUGATES | SEAGEN INC (US) | 2024-08-22 | — | — | US | disclosed |
| CN-114929284-A | Camptothecin peptide conjugates | 西根公司 | 2022-08-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240277860-A1 | CAMPTOTHECIN PEPTIDE CONJUGATES | VIP, DCLRE1A, UACA | CPB2 869/4885NMT2 104/4885NMT1 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.