Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 2/20 | 0.45 |
| ▸ | GNPAT | O15228 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31366730 | 0.95 | OPRD1 (0.53) | OPRM1OPRD1MMEACE | |
| SCHEMBL31419815 | 0.94 | KISS1R (0.48) | BACE1OPRM1OPRD1MMECTSD | |
| SCHEMBL31419810 | 0.94 | KISS1R (0.48) | BACE1OPRM1OPRD1MMECTSD | |
| SCHEMBL29658158 | 0.92 | MME (0.50) | PSMB5OPRM1OPRD1CTSBMME | |
| SCHEMBL29784971 | 0.90 | ALDH1A1 (0.52) | MMEGNPATMMP2MMP7MMP9 | |
| SCHEMBL30123255 | 0.88 | BACE1 (0.53) | BACE1OPRM1OPRD1CTSD | |
| SCHEMBL30054155 | 0.88 | MME (0.56) | PSMB5OPRM1OPRD1MMECTSD | |
| SCHEMBL30055181 | 0.87 | MME (0.49) | BACE1OPRM1OPRD1MMECTSD | |
| SCHEMBL31134971 | 0.87 | MME (0.47) | BACE1OPRM1OPRD1MMECTSD | |
| SCHEMBL31514370 | 0.86 | MME (0.53) | MMEGNPATMMP2MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521504-B | Anti-human EGFR nano antibody and application thereof | 暨南大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-112457405-B | Anti-human EGFR nano antibody and application | 暨南大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-112457404-B | Anti-human EGFR nano antibody and application | 暨南大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-112552402-B | Anti-human EGFR nano antibody and application | 暨南大学 | 2022-08-12 | — | — | CN | disclosed |