Calceolarioside B

Calceolarioside B

SCHEMBL29785210

O=C(/C=C/c1ccc(O)c(O)c1)OC[C@H]1O[C@@H](OCCc2ccc(O)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PRKCA P17252 7/20 1.00
▸ CYP19A1 P11511 3/20 1.00
▸ MMP2 P08253 1/20 0.79
▸ MMP3 P08254 1/20 0.79
▸ MMP9 P14780 1/20 0.79
▸ MMP12 P39900 1/20 0.79
▸ MMP13 P45452 1/20 0.79
▸ KDM1A O60341 2/20 0.69
▸ ALDH1A1 P00352 1/20 0.63
▸ CYP3A4 P08684 1/20 0.63
▸ ALOX15 P16050 1/20 0.63
▸ MAPK1 P28482 1/20 0.63
▸ HSD17B10 Q99714 1/20 0.63
▸ L3MBTL1 Q9Y468 2/20 0.62
▸ BACE1 P56817 1/20 0.62
▸ APP P05067 1/20 0.61
▸ XDH P47989 1/20 0.54
▸ TRPV3 Q8NET8 1/20 0.54
▸ AKR1B1 P15121 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Calceolarioside B SCHEMBL17173771 1.00 PRKCA (1.00) PRKCACYP19A1MMP2MMP3MMP9
Calceolarioside B SCHEMBL30913582 1.00 PRKCA (1.00) PRKCACYP19A1MMP2MMP3MMP9
Calceolarioside B SCHEMBL27983548 1.00 PRKCA (1.00) PRKCACYP19A1MMP2MMP3MMP9
SCHEMBL17173773 0.93 PRKCA (0.86) PRKCACYP19A1MMP2MMP3MMP9
Plantainoside D SCHEMBL23512286 0.91 PRKCA (1.00) PRKCACYP19A1MMP2MMP3MMP9
Plantainoside D SCHEMBL31060761 0.91 PRKCA (1.00) PRKCACYP19A1MMP2MMP3MMP9
SCHEMBL16277000 0.90 PRKCA (0.82) PRKCACYP19A1MMP2MMP3MMP9
SCHEMBL17177798 0.89 PRKCA (0.79) PRKCACYP19A1MMP2MMP3MMP9
Isoacteoside SCHEMBL16689428 0.88 MMP2 (1.00) PRKCACYP19A1MMP2MMP3MMP9
Isoacteoside SCHEMBL19429735 0.88 MMP2 (1.00) PRKCACYP19A1MMP2MMP3MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4606437-A1 COSMETIC COMPOSITIONS TO INHIBIT THE ACTIVITY OF KLF4, TO REDUCE SKIN, HAIR, MUCOUS MEMBRANES AGING LABORATOIRE NATIVE (FR) 2025-08-27 — — EP claimed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 — — WO claimed
CN-113491703-B Application of phenylethanoid glycosides compounds and composition thereof in preparation of medicines for preventing and treating new coronavirus infection 中国科学院上海药物研究所 2023-10-31 — — CN claimed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 — — EP disclosed
EP-4606437-A1 COSMETIC COMPOSITIONS TO INHIBIT THE ACTIVITY OF KLF4, TO REDUCE SKIN, HAIR, MUCOUS MEMBRANES AGING LABORATOIRE NATIVE (FR) 2025-08-27 — — EP disclosed
US-20250250647-A1 STABLE CELL CLONES HARBORING REPLICATING SARS-COV-2 RNA THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN (US) 2025-08-07 — — US disclosed
CN-119523995-A New application of akebia stem phenethyl alcohol glycoside B in preparation of MMP12 inhibitor 上海中医药大学 2025-02-28 — — CN disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 — — WO disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 — — WO disclosed
CN-118325868-A Alpha-L-rhamnosidase EsRha, product thereof and method for producing pharmaceutically active ingredient 北京理工大学 2024-07-12 — — CN disclosed
WO-2024007532-A1 METHOD FOR DETERMINING DISSOLUTION RATES OF EIGHT REPRESENTATIVE COMPONENTS IN DAOCHI PILLS 河北省药品医疗器械检验研究院(河北省化妆品检验研究中心) 2024-01-11 — — WO disclosed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 — — WO disclosed
CN-113491703-B Application of phenylethanoid glycosides compounds and composition thereof in preparation of medicines for preventing and treating new coronavirus infection 中国科学院上海药物研究所 2023-10-31 — — CN disclosed
US-20230046151-A1 SYSTEM FOR PROVIDING CUSTOMIZED COSMETICS LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2023-02-16 — — US disclosed
EP-4123553-A1 SYSTEM FOR PROVIDING CUSTOMIZED COSMETICS LG Household & Health Care Ltd. (KR) 2023-01-25 — — EP disclosed
CN-115505014-A Callicarpa nudiflora extract, preparation method and application thereof 江中药业股份有限公司 2022-12-23 — — CN disclosed
US-20220273748-A1 PLANT FERMENT AND WEIGHT LOSS METHOD FOR USING THE SAME TCI CO., LTD. (TW) 2022-09-01 — — US disclosed
CN-114787851-A Customized cosmetic providing system 株式会社LG生活健康 2022-07-22 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273748-A1 PLANT FERMENT AND WEIGHT LOSS METHOD FOR USING THE SAME FABP6, MGAM, FUCA1 PRKCA 2176/4885CYP19A1 4203/4885MMP2 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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