Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 7/20 | 0.82 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.82 |
| ▸ | MMP2 | P08253 | 1/20 | 0.78 |
| ▸ | MMP3 | P08254 | 1/20 | 0.78 |
| ▸ | MMP9 | P14780 | 1/20 | 0.78 |
| ▸ | MMP12 | P39900 | 1/20 | 0.78 |
| ▸ | MMP13 | P45452 | 1/20 | 0.78 |
| ▸ | KDM1A | O60341 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16276035 | 0.96 | PRKCA (0.75) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL17614820 | 0.95 | PRKCA (0.74) | PRKCACYP19A1MMP2MMP3MMP9 | |
| Calceolarioside B SCHEMBL30913582 | 0.90 | PRKCA (1.00) | PRKCACYP19A1MMP2MMP3MMP9 | |
| Calceolarioside B SCHEMBL17173771 | 0.90 | PRKCA (1.00) | PRKCACYP19A1MMP2MMP3MMP9 | |
| Calceolarioside B SCHEMBL29785210 | 0.90 | PRKCA (1.00) | PRKCACYP19A1MMP2MMP3MMP9 | |
| Calceolarioside B SCHEMBL27983548 | 0.90 | PRKCA (1.00) | PRKCACYP19A1MMP2MMP3MMP9 | |
| Isoacteoside SCHEMBL16689428 | 0.88 | MMP2 (1.00) | PRKCACYP19A1MMP2MMP3MMP9 | |
| Isoacteoside SCHEMBL19429735 | 0.88 | MMP2 (1.00) | PRKCACYP19A1MMP2MMP3MMP9 | |
| Isoacteoside SCHEMBL19429736 | 0.88 | MMP2 (1.00) | PRKCACYP19A1MMP2MMP3MMP9 | |
| Isoacteoside SCHEMBL29372645 | 0.88 | MMP2 (1.00) | PRKCACYP19A1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160082064-A1 | METHOD FOR REGULATING BLOOD GLUCOSE LEVEL | SINPHAR PHARMACEUTICAL CO., LTD. (TW) | 2016-03-24 | — | — | US | disclosed |
| US-20140357581-A1 | METHOD FOR REGULATING BLOOD GLUCOSE LEVEL | SINPHAR PHARMACEUTICAL CO., LTD. (TW) | 2014-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160082064-A1 | METHOD FOR REGULATING BLOOD GLUCOSE LEVEL | SIRT1, HDAC3, GCKR | PRKCA 659/4885CYP19A1 1085/4885MMP2 1830/4885 |
| US-20140357581-A1 | METHOD FOR REGULATING BLOOD GLUCOSE LEVEL | SIRT1, HDAC3, GCKR | PRKCA 659/4885CYP19A1 1085/4885MMP2 1830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.