SCHEMBL29786252

SCHEMBL29786252

CC(C)(C)c1cccc2sc(C(N)=O)nc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
LMNA P02545 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
LIMK1 P53667 1/20 0.37
PARP1 P09874 3/20 0.37
DYRK1A Q13627 2/20 0.36
TMIGD3 P0DMS9 1/20 0.36
ADORA1 P30542 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36
CA2 P00918 1/20 0.35
PDPK1 O15530 1/20 0.35
MAPT P10636 3/20 0.34
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
RECQL P46063 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18742358 0.81 LIMK1 (0.44) ALDH1A1LMNALIMK1PARP1DYRK1A
SCHEMBL5872790 0.80 ALDH1A1 (0.57) ALDH1A1LMNAL3MBTL1TDP1CYP3A4
SCHEMBL1039915 0.78 PDPK1 (0.59) ALDH1A1L3MBTL1LIMK1DYRK1ACA2
SCHEMBL21612925 0.77 TP53 (0.40) ALDH1A1PARP1MAPTKDM4ESMN1; SMN2
SCHEMBL1038566 0.77 TDP1 (0.62) ALDH1A1LMNAL3MBTL1DYRK1ATMIGD3
SCHEMBL3057415 0.76 LMNA (0.57) ALDH1A1LMNATDP1MAPTKDM4E
SCHEMBL3060022 0.76 SMN1; SMN2 (0.57) ALDH1A1LMNAL3MBTL1MAPTKDM4E
SCHEMBL8522568 0.76 CA2 (0.51) LMNATDP1CA2KDM4EKMT2A
SCHEMBL11607734 0.76 ALDH1A1 (0.61) ALDH1A1LMNATDP1CYP3A4CA2
SCHEMBL17489174 0.75 TNF (0.40) ALDH1A1LMNAL3MBTL1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111100013-B Method for preparing tert-butylamine 中国石油化工股份有限公司 2023-03-07 CN disclosed
CN-111825555-B Method for preparing tert-butylamine by using MTBE as raw material 中国石油化工股份有限公司 2023-02-03 CN disclosed
CN-111100009-B Method for preparing tert-butylamine by using MTBE as raw material 中国石油化工股份有限公司 2022-10-11 CN disclosed
CN-111825556-B Preparation method of tert-butylamine 中国石油化工股份有限公司 2022-09-09 CN disclosed
CN-112745224-B Method for preparing tert-butylamine 中国石油化工股份有限公司 2022-09-09 CN disclosed
CN-112745223-B Process for preparing tert-butylamine 中国石油化工股份有限公司 2022-08-12 CN disclosed