Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985781 | 0.89 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2ARXFP1HPGD | |
| SCHEMBL2983520 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KDM4EKMT2AHPGDL3MBTL1 | |
| SCHEMBL2977579 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KDM4EKMT2ARXFP1HPGD | |
| SCHEMBL2974653 | 0.80 | SIGMAR1 (0.42) | ALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL5159160 | 0.77 | MCHR1 (0.36) | ALDH1A1KDM4EHPGDHTTS100A4 | |
| SCHEMBL2985810 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2ARXFP1HPGD | |
| SCHEMBL2985326 | 0.73 | HPGD (0.50) | ALDH1A1KMT2AHPGDHTTMEN1 | |
| SCHEMBL2989313 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2ARXFP1HPGD | |
| SCHEMBL2984696 | 0.72 | HPGD (0.46) | ALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL2989227 | 0.71 | BCHE (0.41) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786328-B2 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2010-08-31 | — | — | US | claimed |
| US-20070281954-A1 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-12-06 | — | — | US | claimed |
| US-7786328-B2 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2010-08-31 | — | — | US | disclosed |
| US-20070281954-A1 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281954-A1 | Cyclohexyl-1,4-diamine compounds | DPYD, PKD1, AOC1 | ALDH1A1 207/4885KDM4E 1010/4885KMT2A 3786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.