Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20472323 | 1.00 | HTR2A (0.41) | HTR2AHTR2CHTR2BPARP10PARP15 | |
| SCHEMBL24018791 | 0.82 | SCN9A (0.39) | HTR2AHTR2CHTR2BPARP10SCN9A | |
| SCHEMBL24180164 | 0.81 | PARP10 (0.43) | HTR2AHTR2CHTR2BPARP10PARP15 | |
| SCHEMBL22389492 | 0.81 | RIPK1 (0.44) | HTR2AHTR2CHTR2BPARP10PARP15 | |
| SCHEMBL22957638 | 0.81 | HTR2A (0.41) | HTR2AHTR2CHTR2BSCN9A | |
| SCHEMBL24018827 | 0.81 | SCN9A (0.38) | HTR2AHTR2CHTR2BPARP10SCN9A | |
| SCHEMBL20472479 | 0.80 | MCHR1 (0.48) | HTR2AHTR2CHTR2BPARP10MCHR1 | |
| SCHEMBL29786629 | 0.80 | MCHR1 (0.48) | HTR2AHTR2CHTR2BPARP10MCHR1 | |
| SCHEMBL22957828 | 0.79 | SCN9A (0.39) | HTR2AHTR2CHTR2BSCN9A | |
| SCHEMBL20472614 | 0.77 | MCHR1 (0.48) | HTR2AHTR2CHTR2BPARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520423-B | Aminotriazolopyridines as kinase inhibitors | 百时美施贵宝公司 | 2022-08-23 | — | — | CN | disclosed |