Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24018791 | 0.87 | SCN9A (0.39) | SCN9ASCN5ARIPK1HTR2AHTR2C | |
| SCHEMBL22957638 | 0.86 | HTR2A (0.41) | SCN9ASCN5ARIPK1HTR2AHTR2C | |
| SCHEMBL22957828 | 0.83 | SCN9A (0.39) | SCN9ASCN5ARIPK1HTR2AHTR2C | |
| SCHEMBL20472323 | 0.81 | HTR2A (0.41) | SCN9AHTR2AHTR2CHTR2BPARP10 | |
| SCHEMBL29786587 | 0.81 | HTR2A (0.41) | SCN9AHTR2AHTR2CHTR2BPARP10 | |
| SCHEMBL22389492 | 0.77 | RIPK1 (0.44) | SCN9ASCN5ARIPK1HTR2AHTR2C | |
| SCHEMBL24180164 | 0.74 | PARP10 (0.43) | SCN9ASCN5AHTR2AHTR2CHTR2B | |
| SCHEMBL28331550 | 0.74 | SCN9A (0.42) | SCN9ASCN5AHTR2AHTR2CHTR2B | |
| SCHEMBL24180086 | 0.72 | HTR2A (0.38) | SCN9ARIPK1HTR2AHTR2CHTR2B | |
| SCHEMBL22390588 | 0.71 | RIPK1 (0.50) | SCN9ARIPK1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3580220-B1 | AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-17 | — | — | EP | disclosed |