SCHEMBL2978906

SCHEMBL2978906

C=C(C(=O)O)c1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
LMNA P02545 3/20 0.39
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
SRD5A2 P31213 1/20 0.39
PTGES O14684 1/20 0.39
ALOX5 P09917 1/20 0.39
HPGD P15428 4/20 0.37
MAPT P10636 4/20 0.37
MCL1 Q07820 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
UTS2R Q9UKP6 2/20 0.36
HTT P42858 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
KMT2A Q03164 3/20 0.36
PKM P14618 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13918064 0.91 HDAC1 (0.45) ALDH1A1SMN1; SMN2HPGDMAPTHDAC1
SCHEMBL4797412 0.89 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2RXRARXRBLMNA
SCHEMBL4237341 0.86 MAPT (0.46) ALDH1A1SMN1; SMN2HPGDMAPTHDAC1
SCHEMBL4237599 0.86 MAPT (0.46) ALDH1A1SMN1; SMN2HPGDMAPTHDAC1
SCHEMBL12151373 0.84 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2RXRARXRBLMNA
SCHEMBL1124581 0.84 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2LMNACES2CES1
SCHEMBL7909102 0.82 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2RXRARXRBLMNA
SCHEMBL27701666 0.82 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2LMNACES2CES1
SCHEMBL2302611 0.80 MEN1 (0.46) ALDH1A1SMN1; SMN2RXRARXRBLMNA
SCHEMBL1416937 0.80 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2CES2CES1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8543037-B2 Image forming apparatus RICOH COMPANY, LTD. (JP) 2013-09-24 US disclosed
US-8420284-B2 Electrophotographic photoreceptor, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2013-04-16 US disclosed
US-8293439-B2 Electrophotographic photorecptor, method of manufacturing electrophotographic photorecptor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2012-10-23 US disclosed
US-20100232831-A1 Electrophotographic Photorecptor, Method Of Manufacturing Electrophotographic Photorecptor, Image Forming Apparatus, And Process Cartridge RICOH COMPANY, LTD. (JP) 2010-09-16 US disclosed
US-20100172670-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2010-07-08 US disclosed
US-20100124712-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2010-05-20 US disclosed