Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 19/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29789992 | 1.00 | WDR5 (0.57) | WDR5CHRM3 | |
| SCHEMBL20896556 | 1.00 | WDR5 (0.57) | WDR5CHRM3 | |
| SCHEMBL20896611 | 1.00 | WDR5 (0.57) | WDR5CHRM3 | |
| SCHEMBL20896835 | 0.88 | WDR5 (0.60) | WDR5 | |
| SCHEMBL29789668 | 0.88 | WDR5 (0.60) | WDR5 | |
| SCHEMBL20896855 | 0.85 | WDR5 (0.59) | WDR5CHRM3 | |
| SCHEMBL29790014 | 0.85 | WDR5 (0.59) | WDR5CHRM3 | |
| SCHEMBL20606478 | 0.85 | WDR5 (0.59) | WDR5CHRM3 | |
| SCHEMBL20606343 | 0.84 | WDR5 (0.58) | WDR5CHRM3 | |
| SCHEMBL29790029 | 0.82 | ALDH1A1 (0.48) | WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195965-B | Inhibitors of WDR5 protein-protein binding | 普罗佩纶治疗公司 | 2022-07-26 | — | — | CN | disclosed |