Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrothiophene SCHEMBL1771645 | 0.95 | — | — | |
| Tetrahydrothiophene SCHEMBL30353979 | 0.95 | — | — | |
| Tetrahydrothiophene SCHEMBL9401846 | 0.94 | NOS1 (0.32) | NOS1NOS2 | |
| Tetrahydrothiophene SCHEMBL599924 | 0.94 | NOS1 (0.32) | NOS1NOS2 | |
| SCHEMBL11104939 | 0.94 | NOS1 (0.32) | NOS1NOS2 | |
| Tetrahydrothiophene SCHEMBL2434343 | 0.94 | — | — | |
| Tetrahydrothiophene SCHEMBL9127 | 0.94 | — | — | |
| SCHEMBL12528494 | 0.94 | NOS1 (0.32) | NOS1NOS2 | |
| Tetrahydrothiophene SCHEMBL3423188 | 0.89 | — | — | |
| SCHEMBL619051 | 0.89 | NOS1 (0.30) | NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174703-A1 | THREE-COORDINATE AU(I) PROBES AND USE IN SELECTIVELY DISRUPTING MITOCHONDRIA IN CANCER CELLS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2024-05-30 | — | — | US | disclosed |
| WO-2022187648-A1 | THREE-COORDINATE AU(I) PROBES AND USE IN SELECTIVELY DISRUPTING MITOCHONDRIA IN CANCER CELLS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2022-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174703-A1 | THREE-COORDINATE AU(I) PROBES AND USE IN SELECTIVELY DISRUPTING MITOCHONDRIA IN CANCER CELLS | TFAM, TUFM, UQCRC1 | NOS1 4154/4885NOS2 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.