SCHEMBL2979064

SCHEMBL2979064

CNC(=O)CN(C(=O)O)C1CCN(Cc2cccc(Oc3ccc(F)cc3)c2)CC1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CCR8 P51685 5/20 0.55
UBE2M P61081 1/20 0.49
DCUN1D1 Q96GG9 1/20 0.49
FAAH O00519 6/20 0.49
CCR3 P51677 1/20 0.49
LTA4H P09960 1/20 0.47
MGLL Q99685 1/20 0.46
DRD2 P14416 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2983168 0.86 CCR8 (0.52) CCR8FAAHCCR3MGLL
SCHEMBL3599977 0.84 CCR3 (0.57) CCR8FAAHCCR3MGLL
SCHEMBL2983164 0.79 CCR8 (0.55) CCR8FAAHCCR3MGLLDRD2
SCHEMBL3591109 0.78 CCR8 (0.71) CCR8FAAHCCR3
SCHEMBL6500525 0.78 CCR8 (0.88) CCR8CCR3
SCHEMBL2982171 0.77 HTR2A (0.52) LTA4HDRD2
SCHEMBL3599975 0.77 CCR8 (0.58) CCR8FAAHCCR3
SCHEMBL27654951 0.76 CHRM4 (0.50) CCR8FAAH
SCHEMBL2967113 0.76 CHRM4 (0.54) CCR8
SCHEMBL2979065 0.76 MMP13 (0.42) CCR8UBE2MDCUN1D1FAAHCCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781590-B2 Piperidinylalkylcarbamate derivatives, methods for their preparation and the therapeutic use thereof as fatty acid amido hydrolase enzyme inhibitors SANOFI-AVENTIS (FR) 2010-08-24 US disclosed
US-20070021403-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS SANOFI-AVENTIS (FR) 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021403-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS FAAH, FAAH2, CNR2 CCR8 2508/4885UBE2M 3836/4885DCUN1D1 4751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.