Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 9/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793043 | 0.94 | TYMP (0.39) | TYMPLMNASMN1; SMN2NPEPPSTP53 | |
| SCHEMBL30173459 | 0.94 | TYMP (0.42) | TYMPLMNASMN1; SMN2NPEPPSTP53 | |
| SCHEMBL29793014 | 0.91 | TYMP (0.43) | TYMPLMNASMN1; SMN2NPEPPSTP53 | |
| SCHEMBL31160200 | 0.89 | TYMP (0.43) | TYMPLMNASMN1; SMN2NPEPPSTP53 | |
| SCHEMBL30173452 | 0.89 | TYMP (0.42) | TYMPLMNASMN1; SMN2NPEPPSTP53 | |
| SCHEMBL9011484 | 0.88 | TYMP (0.37) | TYMPLMNASMN1; SMN2NPEPPSTP53 | |
| SCHEMBL24878603 | 0.86 | TYMP (0.43) | TYMPADORA1 | |
| SCHEMBL668595 | 0.86 | TYMP (0.43) | TYMPADORA1 | |
| SCHEMBL29581997 | 0.86 | TYMP (0.43) | TYMPADORA1 | |
| SCHEMBL25873876 | 0.86 | TYMP (0.43) | TYMPADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4277636-A1 | MODIFIED OLIGONUCLEOTIDES | Alnylam Pharmaceuticals, Inc. (US) | 2023-11-22 | — | — | EP | disclosed |
| WO-2022155418-A9 | MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| WO-2022155418-A1 | MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2022-07-21 | — | — | WO | disclosed |