SCHEMBL30173459

CCN(C(=O)c1ccccc1)c1ncnc2c1ncn2[C@@H]1O[C@H](COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H]1OC

nearest known ligand 0.42

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	TYMP	P19971	10/20	0.42

▸	LMNA	P02545	2/20	0.36

▸	NPEPPS	P55786	2/20	0.34

▸	SMN1; SMN2	Q16637	3/20	0.34

▸	TP53	P04637	2/20	0.34

▸	CYP3A4	P08684	2/20	0.34

▸	ADORA2A	P29274	1/20	0.34

▸	ADORA2B	P29275	1/20	0.34

▸	ANPEP	P15144	1/20	0.34

▸	HIF1A	Q16665	1/20	0.34

▸	ADORA1	P30542	2/20	0.33

▸	HTT	P42858	1/20	0.33

▸	NPC1	O15118	1/20	0.33

▸	RAB9A	P51151	1/20	0.33

▸	PAX8	Q06710	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29793014	0.94	TYMP (0.43)	TYMPLMNANPEPPSSMN1; SMN2TP53
SCHEMBL29792961	0.94	TYMP (0.40)	TYMPLMNANPEPPSSMN1; SMN2TP53
SCHEMBL30173452	0.94	TYMP (0.42)	TYMPLMNANPEPPSSMN1; SMN2TP53
SCHEMBL31160200	0.92	TYMP (0.43)	TYMPLMNANPEPPSSMN1; SMN2TP53
SCHEMBL24878603	0.89	TYMP (0.43)	TYMPADORA1
SCHEMBL29581997	0.89	TYMP (0.43)	TYMPADORA1
SCHEMBL26535891	0.89	TYMP (0.43)	TYMPADORA1
SCHEMBL25873876	0.89	TYMP (0.43)	TYMPADORA1
SCHEMBL668595	0.89	TYMP (0.43)	TYMPADORA1
SCHEMBL26419986	0.89	TYMP (0.40)	TYMPLMNANPEPPSSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023277168-A1	POLYNUCLEOTIDE AND MEDICINAL COMPOSITION	協和キリン株式会社	2023-01-05	—	—	WO	disclosed