Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.42 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23123641 | 1.00 | CYP11B2 (0.43) | CYP11B2SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL31152780 | 0.85 | SMARCA2 (0.55) | SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL1249642 | 0.85 | SMARCA2 (0.55) | SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL23123008 | 0.85 | ALDH1A1 (0.43) | CYP11B2SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL30579527 | 0.81 | DRD2 (0.47) | CYP11B2OXTRAVPR1A | |
| SCHEMBL23124336 | 0.81 | HDAC1 (0.46) | SMARCA2SMARCA4PBRM1GPR119HDAC2 | |
| SCHEMBL29795670 | 0.81 | HDAC1 (0.46) | SMARCA2SMARCA4PBRM1GPR119HDAC2 | |
| SCHEMBL14206383 | 0.81 | CYP11B2 (0.55) | CYP11B2SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL21358377 | 0.80 | CYP11B2 (0.42) | CYP11B2GPR119EGLN2GPR183BCHE | |
| SCHEMBL29519767 | 0.80 | CYP11B2 (0.42) | CYP11B2GPR119EGLN2GPR183BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031532-A1 | SUBSTITUTED BENZIMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | Bial-R&D Investments, S.A. (PT) | 2022-07-27 | — | — | EP | disclosed |