Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23213399 | 1.00 | GAA (0.55) | GAANPSR1CYP1A2KDM4EPKM | |
| SCHEMBL29739598 | 0.89 | CYP1A2 (0.59) | GAACYP1A2KDM4EALDH1A1FAAH | |
| SCHEMBL10262389 | 0.86 | RAB9A (0.59) | MAPK1GSK3BDYRK1AKMT2AMEN1 | |
| SCHEMBL4149757 | 0.85 | CYP2D6 (0.56) | GAANPSR1KDM4EPKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL4508721 | 0.85 | NPC1 (0.57) | ALDH1A1MAPK1GSK3BDYRK1AKMT2A | |
| SCHEMBL19696298 | 0.84 | CSF1R (0.53) | GAANPSR1KDM4ECHRM3CHRM4 | |
| SCHEMBL29796156 | 0.84 | USP30 (0.50) | CYP1A2 | |
| SCHEMBL23213657 | 0.84 | USP30 (0.50) | CYP1A2 | |
| SCHEMBL10259928 | 0.83 | ALDH1A1 (0.55) | GAANPSR1KDM4EALDH1A1GSK3B | |
| SCHEMBL10259628 | 0.82 | MTNR1B (0.49) | KDM4EPKMGSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041231-A1 | ISOINDOLINONE COMPOUNDS | Monte Rosa Therapeutics AG (CH) | 2022-08-17 | — | — | EP | disclosed |