Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 17/20 | 0.67 |
| ▸ | CTSD | P07339 | 2/20 | 0.59 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29798303 | 0.95 | BACE1 (0.64) | BACE1CTSDBACE2 | |
| SCHEMBL29798066 | 0.94 | BACE1 (0.61) | BACE1CTSDBACE2LTA4H | |
| SCHEMBL30052981 | 0.92 | LTA4H (0.66) | BACE1CTSDBACE2LTA4H | |
| SCHEMBL29798170 | 0.90 | LTA4H (0.61) | BACE1LTA4H | |
| SCHEMBL29530803 | 0.90 | BACE1 (0.56) | BACE1CTSDBACE2LTA4H | |
| SCHEMBL30037947 | 0.90 | OPRM1 (0.60) | BACE1CTSDBACE2 | |
| SCHEMBL9848664 | 0.89 | OPRD1 (0.61) | BACE1CTSDBACE2 | |
| SCHEMBL30419543 | 0.89 | BACE1 (0.57) | BACE1CTSDBACE2 | |
| SCHEMBL31556143 | 0.89 | BACE1 (0.58) | BACE1CTSDBACE2LTA4H | |
| SCHEMBL9848690 | 0.88 | OPRD1 (0.62) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220259265-A1 | Inhibitors and Use Thereof in Cancer Treatment | THE UNIVERSITY OF SYDNEY (AU) | 2022-08-18 | — | — | US | disclosed |