Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 19/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 19/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.82 |
| ▸ | HTR1A | P08908 | 1/20 | 0.82 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.82 |
| ▸ | HTR2A | P28223 | 1/20 | 0.82 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.82 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.82 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.82 |
| ▸ | HTR2B | P41595 | 1/20 | 0.82 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.82 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153255 | 1.00 | ADRB1 (1.00) | ADRB1ADRB2CHRM2HTR1AADRA2A | |
| SCHEMBL2988139 | 1.00 | ADRB1 (1.00) | ADRB1ADRB2CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL152317 | 0.99 | ADRB1 (0.98) | ADRB1ADRB2CHRM2HTR1AADRA2A | |
| SCHEMBL154839 | 0.94 | ADRB1 (0.89) | ADRB1ADRB2CHRM2HTR1AADRA2A | |
| SCHEMBL2974709 | 0.94 | ADRB1 (0.89) | ADRB1ADRB2CHRM2HTR1AADRA2A | |
| SCHEMBL4709183 | 0.94 | ADRB2 (0.95) | ADRB1ADRB2CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL153897 | 0.93 | ADRB1 (0.88) | ADRB1ADRB2CHRM2HTR1AADRA2A | |
| SCHEMBL154335 | 0.92 | ADRB1 (1.00) | ADRB1ADRB2CHRM2HTR1AADRA2A | |
| SCHEMBL153533 | 0.92 | ADRB1 (1.00) | ADRB1ADRB2CHRM2HTR1AADRA2A | |
| SCHEMBL2989571 | 0.92 | ADRB1 (1.00) | ADRB1ADRB2CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110840847-B | Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases | 沃泰克斯药物股份有限公司 | 2022-07-29 | — | — | CN | disclosed |