Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.95 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.95 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.81 |
| ▸ | HTR1A | P08908 | 1/20 | 0.81 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.81 |
| ▸ | HTR2A | P28223 | 1/20 | 0.81 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.81 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.81 |
| ▸ | HTR2B | P41595 | 1/20 | 0.81 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.81 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153077 | 0.97 | ADRB2 (1.00) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL29737207 | 0.97 | ADRB2 (1.00) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL560927 | 0.97 | ADRB2 (1.00) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL153900 | 0.97 | ADRB2 (0.98) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL561414 | 0.97 | ADRB2 (0.98) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL29798972 | 0.94 | ADRB1 (1.00) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL2988139 | 0.94 | ADRB1 (1.00) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL153255 | 0.94 | ADRB1 (1.00) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL152317 | 0.93 | ADRB1 (0.98) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| Succinic Acid SCHEMBL561453 | 0.93 | ADRB2 (0.91) | ADRB2ADRB1CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007772-A1 | THIAZOLYL-DIHYDROQUINAZOLINES | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007115932-A1 | THIAZOLYL-DIHYDROQUINAZOLINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |