Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604328 | 0.85 | TDP1 (0.47) | FAAHMCL1TDP1KMT2AMEN1 | |
| SCHEMBL10607879 | 0.81 | FAAH (0.52) | FAAHMCL1MMP1MMP2MMP3 | |
| SCHEMBL28886374 | 0.80 | MCL1 (0.50) | FAAHMCL1TDP1KMT2AMEN1 | |
| SCHEMBL10608575 | 0.77 | FAAH (0.59) | FAAHMCL1KMT2A | |
| SCHEMBL8371300 | 0.77 | TDP1 (0.64) | TDP1KMT2AKDM4EKDM6BKDM5C | |
| SCHEMBL13379743 | 0.77 | TDP1 (0.64) | TDP1KMT2AKDM4EKDM6BKDM5C | |
| SCHEMBL8984748 | 0.77 | TDP1 (0.64) | TDP1KMT2AKDM4EKDM6BKDM5C | |
| SCHEMBL30255411 | 0.77 | TDP1 (0.64) | TDP1KMT2AKDM4EKDM6BKDM5C | |
| SCHEMBL31303962 | 0.77 | ADH1B (0.39) | FAAHMCL1KMT2AMEN1 | |
| SCHEMBL23729623 | 0.76 | FAAH (0.69) | FAAHKMT2AMEN1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957219-B | Degradation agent for targeted degradation of Gli1 protein, preparation method and application thereof | 苏州大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-114957219-A | Degradation agent for targeted degradation of Gli1 protein and preparation method and application thereof | 苏州大学 | 2022-08-30 | — | — | CN | disclosed |