Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19477899 | 0.92 | FAAH (0.60) | FAAHGAAEPHX2HSP90AA1DNM1 | |
| SCHEMBL10064157 | 0.89 | FAAH (0.86) | FAAHGAAEPHX2HSP90AA1DNM1 | |
| SCHEMBL13268369 | 0.89 | FAAH (0.86) | FAAHGAAEPHX2HSP90AA1DNM1 | |
| SCHEMBL9618659 | 0.86 | FAAH (0.81) | FAAHGAAEPHX2HSP90AA1DNM1 | |
| SCHEMBL17776416 | 0.85 | CASP2 (0.59) | FAAHEPHX2DNM1CASP2MEN1 | |
| SCHEMBL15452323 | 0.83 | FAAH (0.69) | FAAHGAAEPHX2HSP90AA1DNM1 | |
| SCHEMBL16217890 | 0.83 | RECQL (0.52) | FAAHGAAEPHX2HSP90AA1DNM1 | |
| SCHEMBL15452322 | 0.83 | FAAH (0.69) | FAAHGAAEPHX2HSP90AA1DNM1 | |
| SCHEMBL2343012 | 0.82 | FAAH (1.00) | FAAHEPHX2HSP90AA1DNM1CASP2 | |
| SCHEMBL4147161 | 0.82 | FAAH (1.00) | FAAHEPHX2HSP90AA1DNM1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |