Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | TDO2 | P48775 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27214168 | 1.00 | MEN1 (0.60) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL7820257 | 0.87 | KDM4E (0.61) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL11973794 | 0.85 | PSMD14 (0.61) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL18434761 | 0.83 | KDM4E (0.57) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL19220855 | 0.81 | MAPT (0.48) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL6537393 | 0.80 | MEN1 (0.54) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL11701285 | 0.79 | MAPT (0.72) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL8544930 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL4642926 | 0.78 | MEN1 (0.67) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL6538214 | 0.78 | MAPT (0.77) | MEN1KMT2AKDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4291555-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-116806218-A | Sulfonamide and its use for the treatment of parasitic helminth infections and diseases | 新基公司 | 2023-09-26 | — | — | CN | disclosed |
| WO-2022173727-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-08-18 | — | — | WO | disclosed |