Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 4/20 | 0.78 |
| ▸ | SLC40A1 | Q9NP59 | 10/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.61 |
| ▸ | CKS1B | P61024 | 1/20 | 0.60 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26964245 | 1.00 | GLO1 (0.78) | GLO1SLC40A1MEN1KMT2ATDP1 | |
| SCHEMBL7197593 | 0.86 | SLC40A1 (1.00) | GLO1SLC40A1MEN1KMT2ATDP1 | |
| SCHEMBL30925561 | 0.86 | MEN1 (0.74) | GLO1SLC40A1MEN1KMT2ATDP1 | |
| SCHEMBL11995657 | 0.85 | SLC40A1 (1.00) | GLO1SLC40A1MEN1KMT2ATDP1 | |
| SCHEMBL22076984 | 0.84 | MEN1 (1.00) | GLO1SLC40A1MEN1KMT2ATDP1 | |
| SCHEMBL13633886 | 0.84 | MEN1 (1.00) | GLO1SLC40A1MEN1KMT2ATDP1 | |
| SCHEMBL30925544 | 0.84 | SLC40A1 (0.74) | GLO1SLC40A1MEN1KMT2ATDP1 | |
| SCHEMBL27214179 | 0.84 | SLC40A1 (0.74) | GLO1SLC40A1MEN1KMT2ATDP1 | |
| SCHEMBL13633861 | 0.83 | SLC40A1 (0.73) | GLO1SLC40A1MEN1KMT2ATDP1 | |
| SCHEMBL30854819 | 0.83 | CXCR2 (0.77) | SLC40A1MEN1KMT2ATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4291555-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-116806218-A | Sulfonamide and its use for the treatment of parasitic helminth infections and diseases | 新基公司 | 2023-09-26 | — | — | CN | disclosed |
| WO-2022173727-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-08-18 | — | — | WO | disclosed |