Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.77 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.77 |
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.69 |
| ▸ | RELA | Q04206 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29255671 | 1.00 | CXCR2 (0.77) | CXCR2CXCR4SLC40A1MEN1KMT2A | |
| SCHEMBL13633861 | 0.88 | SLC40A1 (0.73) | CXCR2CXCR4SLC40A1MEN1KMT2A | |
| SCHEMBL11973706 | 0.87 | SLC40A1 (0.78) | CXCR2CXCR4SLC40A1MEN1KMT2A | |
| SCHEMBL4470146 | 0.85 | MEN1 (0.71) | CXCR2CXCR4SLC40A1MEN1KMT2A | |
| SCHEMBL7197593 | 0.84 | SLC40A1 (1.00) | CXCR2CXCR4SLC40A1MEN1KMT2A | |
| SCHEMBL13633886 | 0.84 | MEN1 (1.00) | CXCR2CXCR4SLC40A1MEN1KMT2A | |
| SCHEMBL11973085 | 0.83 | NFKBIA (0.80) | CXCR2CXCR4SLC40A1MEN1KMT2A | |
| SCHEMBL4484159 | 0.83 | SLC40A1 (0.71) | CXCR2CXCR4SLC40A1MEN1KMT2A | |
| SCHEMBL29800829 | 0.83 | GLO1 (0.78) | CXCR2CXCR4SLC40A1MEN1KMT2A | |
| SCHEMBL26964245 | 0.83 | GLO1 (0.78) | CXCR2CXCR4SLC40A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865886-B | N- (quinoline-8-yl) quinoline-8-sulfonamide compound and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-117865886-A | N- (quinoline-8-yl) quinoline-8-sulfonamide compound and application thereof | 中国药科大学 | 2024-04-12 | — | — | CN | disclosed |