Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 10/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | NTSR2 | O95665 | 7/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29569246 | 0.96 | NTSR1 (0.44) | NTSR1PTPN1OPRD1NTSR2SORT1 | |
| SCHEMBL29801129 | 0.93 | PTPN1 (0.45) | NTSR1PTPN1OPRD1F2 | |
| SCHEMBL29800893 | 0.93 | NTSR1 (0.54) | NTSR1PTPN1OPRD1NTSR2F2 | |
| SCHEMBL29399877 | 0.92 | NTSR1 (0.46) | NTSR1PTPN1OPRD1NTSR2SORT1 | |
| SCHEMBL31067246 | 0.92 | PTPN1 (0.43) | NTSR1PTPN1OPRD1NTSR2XIAP | |
| SCHEMBL29800934 | 0.91 | PTPN1 (0.42) | NTSR1PTPN1OPRD1XIAP | |
| SCHEMBL31067238 | 0.90 | NTSR1 (0.50) | NTSR1PTPN1OPRD1NTSR2SORT1 | |
| SCHEMBL29904041 | 0.89 | APLNR (0.41) | NTSR1PTPN1OPRD1 | |
| SCHEMBL29800494 | 0.88 | OPRM1 (0.44) | OPRD1 | |
| SCHEMBL30493464 | 0.88 | APLNR (0.42) | PTPN1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422799-B | Docetaxel liver cancer-resisting targeted prodrug and medicinal application thereof | 复旦大学 | 2022-07-29 | — | — | CN | claimed |
| CN-109422799-B | Docetaxel liver cancer-resisting targeted prodrug and medicinal application thereof | 复旦大学 | 2022-07-29 | — | — | CN | disclosed |